Detalhe da pesquisa
1.
Dupilumab in patients with chronic spontaneous urticaria (LIBERTY-CSU CUPID): Two randomized, double-blind, placebo-controlled, phase 3 trials.
J Allergy Clin Immunol
; 2024 Feb 29.
Artigo
Inglês
| MEDLINE | ID: mdl-38431226
2.
Passive Prophylactic Administration with a Single Dose of Anti-Fel d 1 Monoclonal Antibodies REGN1908-1909 in Cat Allergen-induced Allergic Rhinitis: A Randomized, Double-Blind, Placebo-controlled Clinical Trial.
Am J Respir Crit Care Med
; 204(1): 23-33, 2021 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33651675
3.
Efficacy of Dupilumab in a Phase 2 Randomized Trial of Adults With Active Eosinophilic Esophagitis.
Gastroenterology
; 158(1): 111-122.e10, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31593702
4.
Clinical and immunological evaluation of cat-allergic asthmatics living with or without a cat.
Clin Exp Allergy
; 51(12): 1624-1633, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34599624
5.
Dupilumab suppresses type 2 inflammatory biomarkers across multiple atopic, allergic diseases.
Clin Exp Allergy
; 51(7): 915-931, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34037993
6.
A novel patient-reported outcomes instrument assessing the side effects of peanut oral immunotherapy.
Ann Allergy Asthma Immunol
; 126(1): 61-68, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32745610
7.
Dupilumab treatment in adults with moderate-to-severe atopic dermatitis.
N Engl J Med
; 371(2): 130-9, 2014 Jul 10.
Artigo
Inglês
| MEDLINE | ID: mdl-25006719
8.
Dupilumab in persistent asthma with elevated eosinophil levels.
N Engl J Med
; 368(26): 2455-66, 2013 Jun 27.
Artigo
Inglês
| MEDLINE | ID: mdl-23688323
9.
Effect of Subcutaneous Dupilumab on Nasal Polyp Burden in Patients With Chronic Sinusitis and Nasal Polyposis: A Randomized Clinical Trial.
JAMA
; 315(5): 469-79, 2016 Feb 02.
Artigo
Inglês
| MEDLINE | ID: mdl-26836729
10.
Sarilumab for the treatment of ankylosing spondylitis: results of a Phase II, randomised, double-blind, placebo-controlled study (ALIGN).
Ann Rheum Dis
; 74(6): 1051-7, 2015 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-24550171
11.
Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis.
J Allergy Clin Immunol
; 134(6): 1293-1300, 2014 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-25482871
12.
Sarilumab, a fully human monoclonal antibody against IL-6Rα in patients with rheumatoid arthritis and an inadequate response to methotrexate: efficacy and safety results from the randomised SARIL-RA-MOBILITY Part A trial.
Ann Rheum Dis
; 73(9): 1626-34, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-24297381
13.
Long-term safety and efficacy of rilonacept in patients with systemic juvenile idiopathic arthritis.
Arthritis Rheum
; 65(9): 2486-96, 2013 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-23754188
14.
Rilonacept (interleukin-1 trap) in the prevention of acute gout flares during initiation of urate-lowering therapy: results of a phase II randomized, double-blind, placebo-controlled trial.
Arthritis Rheum
; 64(3): 876-84, 2012 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-22223180
15.
Pharmacokinetics and Concentration-Response of Dupilumab in Patients With Seasonal Allergic Rhinitis.
J Clin Pharmacol
; 62(5): 689-695, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-34791679
16.
REGN1908-1909 monoclonal antibodies block Fel d 1 in cat allergic subjects: Translational pharmacokinetics and pharmacodynamics.
Clin Transl Sci
; 14(6): 2440-2449, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34437752
17.
Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Dupilumab in Healthy Adult Subjects.
Clin Pharmacol Drug Dev
; 9(6): 742-755, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32348036
18.
Safety and pharmacokinetics of subcutaneously administered rilonacept in patients with well-controlled end-stage renal disease (ESRD).
J Clin Pharmacol
; 50(7): 835-41, 2010 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-20035038
19.
Rilonacept--CAPS and beyond.
Ann N Y Acad Sci
; 1182: 124-34, 2009 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-20074281